Phentermine hcl 37.5 mg tab

By | 26.01.2018

phentermine hcl 37.5 mg tab

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Patients should be advised to report immediately any deterioration in exercise tolerance. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Phentermine hydrochloride tablets USP Bontril Bontril Pdm Contrave Desoxyn. WEEK 1 WEIGH IN PHENTERMINE 37.5MG

Use caution when administering phentermine to patients with renal impairment [ see Clinical Pharmacology Phentermine is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program.

Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times than recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG.

Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia. Manifestations of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states.

Fatigue and depression usually follow the central stimulation. Cardiovascular effects include tachycardia, arrhythmia, hypertension or hypotension, and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea and abdominal cramps. Overdosage of pharmacologically similar compounds has resulted in fatal poisoning usually terminates in convulsions and coma. Management of acute phentermine hydrochloride intoxication is largely symptomatic and includes lavage and sedation with a barbiturate.

Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard. Acidification of the urine increases phentermine excretion. The most severe manifestation of chronic intoxications is psychosis, often clinically indistinguishable from schizophrenia. See Drug Abuse and Dependence 9. The structural formula is as follows:. Phentermine hydrochloride is a white, odorless, hygroscopic, crystalline powder which is soluble in water and lower alcohols, slightly soluble in chloroform and insoluble in ether.

Phentermine hydrochloride, an anorectic agent for oral administration, is available as a tablet containing Phentermine hydrochloride tablets contain the inactive ingredients: Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics. Typical actions of amphetamines include central nervous system stimulation and elevation of blood pressure.

Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for. Following the administration of phentermine, phentermine reaches peak concentrations C max after 3 to 4. Exposure increases can be expected in patients with renal impairment. Use caution when administering phentermine to patients with renal impairment.

In a single-dose study comparing the exposures after oral administration of a combination capsule of 15 mg phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg phentermine capsule or a 92 mg topiramate capsule, there is no significant topiramate exposure change in the presence of phentermine. Studies have not been performed with phentermine to determine the potential for carcinogenesis, mutagenesis or impairment of fertility.

In relatively short-term clinical trials, adult obese subjects instructed in dietary management and treated with "anorectic" drugs lost more weight on the average than those treated with placebo and diet. The magnitude of increased weight loss of drug-treated patients over placebo-treated patients is only a fraction of a pound a week. The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks.

The possible origins of the increased weight loss due to the various drug effects are not established. The amount of weight loss associated with the use of an "anorectic" drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugs prescribed, such as the physician-investigator, the population treated and the diet prescribed. Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss.

The natural history of obesity is measured over several years, whereas the studies cited are restricted to a few weeks' duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited. Phentermine hydrochloride tablets USP Patients must be informed that phentermine hydrochloride is a short-term a few weeks adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity, and that coadministration of phentermine with other drugs for weight loss is not recommended [ see Indications and Usage 1 and Warnings and Precautions 5.

Patients must be instructed on how much phentermine to take, and when and how to take it [ see Dosage and Administration 2 ]. Advise pregnant women and nursing mothers not to use phentermine [ see Use in Specific Populations 8. The risks include, but are not limited to:. Tell patients to keep phentermine in a safe place to prevent theft, accidental overdose, misuse or abuse.

Selling or giving away phentermine may harm others and is against the law. DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed. DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImage , we no longer display the RxImage pill images associated with drug labels.

We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. NDC National Drug Code - Each drug product is assigned this unique number which can be found on the drug's outer packaging. Drug Label Information Updated June 29, If you are a consumer or patient please visit this version.

These highlights do not include all the information needed to use phentermine hydrochloride tablets USP safely and effectively. See full prescribing information for phentermine hydrochloride tablets USP. Phentermine should be discontinued in case of new, unexplained symptoms of dyspnea, angina pectoris, syncope or lower extremity edema.

If this occurs, phentermine should be discontinued. The recommended dose should not be exceeded. Risk of hypertensive crisis. Requirements may be altered. Hypotensive effect may be decreased by phentermine. Discontinue drug or nursing taking into consideration importance of drug to mother. Safety and effectiveness not established. Due to substantial renal excretion, use with caution. Below is a chart of body mass index BMI based on various heights and weights.

Metric conversions are as follows: Helps you lose weight. Adipex-P phentermine is not a first choice medicine for weight loss because it is associated with an increased risk for side effects and abuse potential. However, it can be used as a short-term treatment option if other similar medicines don't work. Take this medicine only as directed by your doctor.

Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If you take too much of this medicine, it may become habit-forming causing mental or physical dependence. This medicine is available in four forms: Carefully follow the dosing instructions for the form you are using.

Take the disintegrating tablet with or without food. Make sure your hands are dry before touching the tablet. Place the tablet on the top of your tongue right after removing it from the bottle. It should melt quickly. After the tablet has melted, swallow or take a sip of water. Carefully follow your doctor's instructions for a reduced-calorie diet plan and regular exercise. Talk with your doctor before starting an exercise program.

To avoid trouble with sleeping, take the last dose of the day about 4 to 6 hours before bedtime, unless your doctor tells you otherwise. Adipex-P phentermine can increase the blood pressure in your lungs, which can be very dangerous to your health since it can cause blood clots to form. Tell your doctor right away if you have trouble breathing, chest pain, swelling in your legs, or a lowered ability in how much you can normally exercise. Your body can get used to Adipex-P phentermine and it can become less effective within a few weeks of using it.

Taking more Adipex-P phentermine than what your doctor prescribed will not help you lose weight faster but will instead raise your risk of experiencing physical dependence and side effects. Also, the longer you use the medicine, the more likely you are to potentially abuse it. Talk to your doctor or pharmacist if you think Adipex-P phentermine is not working as well as before for you. Adipex-P phentermine can make heart disease worse and raise the risk of sudden death. Talk to your doctor about other treatment options if you currently have or have a history of an irregular heartbeat, heart failure, chest pain, heart attack, stroke, uncontrolled high blood pressure, or heart valve disease.

Adipex-P phentermine can raise your blood pressure. Talk to your doctor if you have or think you have high blood pressure. Don't take Adipex-P phentermine with other weight loss medicines prescription, over-the-counter, or herbal products because the combinations might not be safe or effective. Talk to your doctor or pharmacist if you have concerns about the medicines you are taking.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.

Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Do not double doses. GoodRx respects your privacy and we do not sell your personal information. By subscribing to emails, you agree to our terms of use and privacy policy. Phentermine Adipex-P is an inexpensive drug used to decrease appetite.


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