How was your experience with Phentermine? The rates of cardiovascular death and death from any cause were not increased. You must select a newsletter to subscribe to. This may help you eat less, which would aid in weight loss. Phentermine -topiramate carries risks of several serious side effects. You may not lose weight.
Well absorbed from the gastrointestinal GI tract; resin absorbed slower. Excreted unchanged in urine. C apsules as hydrochloride: PO A dipex -P: Advanced arteriosclerosis, agitated states, cardiovascular disease, concurrent use or within 14 days of discontinuation of MAOI therapy, glaucoma, history of drug abuse, hypertension moderate-to-severe , hyperthyroidism, hypersensitivity to phentermine or sympathomimetic amines.
Restlessness, insomnia, tremor, palpitations, tachycardia, elevation in blood pressure, headache, dizziness, dry mouth, unpleasant taste, diarrhea or constipation, changes in libido. Primary pulmonary hypertension PPH , psychotic episodes, and valvular heart disease rarely occur. Avoid tasks that require mental alertness or motor skills until response to the drug is established.
Sequeira, in Side Effects of Drugs Annual , In 57 men and women 30 taking Fen—Phen and 27 controls matched for BMI chamber dimensions, wall motion, diastolic function, valvular abnormalities, left ventricular ejection fraction, and pulmonary artery pressures were measured 96 c. Those taking Fen—Phen were studied shortly after they stopped taking it and again 6—12 months later.
The results in these subjects were then compared with the findings in randomly selected cardiac patients with heart disease that was not caused by Fen—Phen. The number of people with aortic regurgitation fell with time after the withdrawal of Fen—Phen. However, among those who continued to have aortic regurgitation, there was an increase in the number of those who progressed from mild to moderate regurgitation, with an associated increase in left ventricular end-diastolic and end-systolic dimensions and left ventricular ejection fraction.
The incidence of tricuspid and mitral regurgitation fell with time, while pulmonic and aortic regurgitation tended to increase or become more severe when present. Dilatation of the pulmonary ring, resulting from raised pulmonic pressures, with subsequent pulmonary regurgitation and reduced pulmonary artery pressures, appears to be a functional change in the hearts of these individuals with unknown long-term consequences.
Adult and Pediatric Seventh Edition , The dose combinations are: Both phentermine and topiramate alone cause weight loss and are available as generics, although the specific mechanism of either is not known. Similarly, the weight-loss mechanism of the combination is not known but is attributed to a reduction in appetite. In clinical studies, phentermine -topiramate reduced body weight by 8. Phentermine -topiramate carries risks of several serious side effects.
Notably, topiramate is a recognized teratogen, at least at the higher doses used for the treatment of epilepsy. The combination of phentermine -topiramate carries a warning of birth defects cleft lip and palate in the offspring of pregnant women taking the combination therapy. Pregnant women should not take the drug, nor should women who are trying to conceive or are at risk for becoming pregnant. The combination is only available through restricted pharmacies as Qsymia.
Several drugs approved for treatment of diabetes also cause weight loss; these include metformin, pramlintide, and the GLP-1 agonists, exenatide and liraglutide. Bupropion, approved for the treatment of depression, may be useful in treating obesity. A combination of bupropion and naltrexone is currently under consideration for approval pending additional safety studies. Targets of investigational therapies include the melanocortin 4 receptor and others.
There is sufficient turnover in these clinical development programs that any list is almost immediately out of date and incomplete. Readers should refer to a recent review for a more complete discussion of current developmental candidates. The biggest limitation of lifestyle interventions is the tachyphylaxis; most patients return to their initial weight within 5 years. It remains to be determined if pharmacotherapy can be used to assist with weight maintenance after weight reduction.
Bello 1 , in Side Effects of Drugs Annual , A year-old woman taking phentermine She typically took phentermine intermittently, two to three times a week. However, for the last 2 weeks she increased the medication to two to three times daily. She had a pack-year history of smoking tobacco. Upon arrival her vital signs were within the normal range but CT scans reveal a subarachnoid hemorrhage SAH in the basal cistern.
Patient remained stable during her 9-day hospitalization. At her 6-week follow-up she was stable and had resumed a normal routine. The authors suggest the cause of SAH was likely secondary to a suddenly escalation in phentermine [ 60 A]. Nervous system A year-old woman took phentermine , developed altered mental status, and had two generalized seizures [ 77 A ]. Phentermine comes in tablet and capsule form.
Phentermine also is available as an orally disintegrating tablet and is usually taken in the morning, with or without food. Phentermine is a prescription medicine used to help adults lose weight. It is taken for a limited amount of time by overweight people who are exercising and eating a low-calorie diet. Phentermine can cause primary pulmonary hypertension, a rare but serious and sometimes fatal side effect.
This is a condition where the pressure of the arteries in your lungs increases, causing more pressure on your heart which can lead to heart failure and death. The first symptoms is often shortness of breath or lightheadedness during activity. This is not a complete list of phentermine side effects. Ask your doctor or pharmacist for more information. Tell your doctor about all the medicines you take including prescription and nonprescription medications, vitamins, and herbal supplements.
Especially tell your doctor if you take:. This is not a complete list of phentermine drug interactions. Phentermine may impair the ability of the patient to drive or operate heavy machinery. Do not drive or operate heavy machinery until you know how phentermine affects you. Risk of Abuse and Dependence. Phentermine should not be stopped all of a sudden especially if phentermine dose is high. This can lead to serious problems. While there are no specific phentermine food interactions, you should avoid drinking large amounts of beverages containing caffeine coffee, tea, colas or eating large amounts of chocolate while taking phentermine as caffeine can increase the side effects of this medicine.
Before taking phentermine, tell your doctor about all of your medical conditions. Especially tell your doctor if you:. Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
Phentermine falls into category X. Phentermine should not be used during pregnancy because weight loss offers no potential benefit to a pregnant woman and may result in fetal harm. There are no situations where the benefits of the medication for the mother outweigh the risks of harm to the baby. These medicines should never be used by pregnant women. It is not known if phentermine crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication.
Your doctor and you will decide if the benefits outweigh the risk of using phentermine. Phentermine comes in tablet, capsule. Phentermine also is available as an orally disintegrating tablet form and is usually taken in the morning, with or without food. Taking phentermine in the evening can cause insomnia trouble falling asleep or staying asleep , so phentermine should be taken in the morning. With dry hands, gently remove the Suprenza phentermine hydrochloride ODT tablet from the bottle.
Immediately place the tablet on top of the tongue where it will dissolve, then swallow with or without water. If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of phentermine at the same time. Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.
The dose your doctor recommends will be individualized to obtain an adequate response with the lowest effective dose. The typical adult dose is For some patients, Suprenza is available as 15 mg, 30 mg, or If you take too much phentermine, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. Phentermine is a controlled medication used for weight loss. Try to avoid drinking large amounts of beverages containing caffeine.
Avoid drinking alcohol while taking this medication. Common side effects of phentermine include dry mouth, fast heart beat, insomnia, and dizziness. Patient Ratings for Phentermine.