Would you like to switch the language? Before having surgery, tell your doctor or dentist that you are using this medication. What is phentermine HCL, and is it safe in helping me to lose weight? Phentermine is approved for the short term treatment few weeks of obesity. You should not take Adipex-P if you have a history of heart disease coronary artery disease, heart rhythm problems, congestive heart failure, stroke , severe or uncontrolled high blood pressure, overactive thyroid, glaucoma, a history of pulmonary hypertension, if you are in an agitated state, or if you have a history of drug or alcohol abuse. This drug should not be used with certain medications because very serious interactions may occur.
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|PRESCRIPTION DIET PILLS PHENTERMINE 37.5 SIDE EFFECTS||Adipex-P phentermine is an appetite suppressant to help reduce weight in obese patients when phentermine short-term and combined with adipex, diet, and behavioral modification. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Adipex-P, especially:. PPH adipex a rare, but fatal lung disease. Add diet cups of raw carrots, jicama, bell pepper strips and phentermine small apple, with a glass typical phentermine results long-term care water. The combination was extremely effective in helping people lose weight very fast, but it also pills harmful for some people who took it. It was scientifically developed in a lab …. To help you diet, take it at the pills time s each day.|
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It was first introduced in , and became part of the drug combination fen-phen that was withdrawn from the market in due to the fenfluramine component damaging people's heart valves. Different formulations of phentermine as a single agent are available under various brand names, in many countries. Phentermine is used for a short period of time to promote weight loss, if exercise and calorie reduction are not sufficient, and in addition to exercise and calorie reduction.
Phentermine is approved for up to 12 weeks of use and most weight loss occurs in the first weeks. Phentermine use is contraindicated in those who: Phentermine may decrease the effect of drugs like clonidine , methyldopa , and guanethidine. Drugs to treat hypothyroidism may increase the effect of phentermine. Rare cases of pulmonary hypertension and cardiac valvular disease have been reported. There is no evidence that phentermine is safe for women who are pregnant.
Other adverse effects include: Phentermine has some similarity in its pharmacodynamics with its parent compound, amphetamine , as they both are TAAR1 agonists ,  where the activation of TAAR1 in monoamine neurons facilitates the efflux or, release into the synapse, of these neurochemicals; at clinically relevant doses, phentermine primarily acts as a releasing agent of norepinephrine in neurons , although, to a lesser extent, it releases dopamine and serotonin into synapses as well.
The primary mechanism of phentermine's action in treating obesity is the reduction of hunger perception, which is a cognitive process mediated primarily through several nuclei within the hypothalamus in particular, the lateral hypothalamic nucleus , arcuate nucleus , and ventromedial nucleus. Outside the brain, phentermine releases norepinephrine and epinephrine — also known as noradrenaline and adrenaline respectively — causing fat cells to break down stored fat as well.
In , phentermine first received approval from the United States FDA as an appetite-suppressing drug. Phentermine was marketed with fenfluramine or dexfenfluramine as a combination appetite suppressant and fat burning agent under the popular name fen-phen. In , after 24 cases of heart valve disease in fen-phen users, fenfluramine and dexfenfluramine were voluntarily taken off the market at the request of the FDA. Phentermine is still available by itself in most countries, including the US. In contrast, amphetamine preparations are classified as Schedule II controlled substances.
Phentermine can be produced from benzaldehyde and 2-nitropropane as follows: From Wikipedia, the free encyclopedia. S4 Prescription only CA: NC Cc1ccccc1 C C. FDA pregnancy category X. Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use Adipex-P if you are pregnant. Pregnancy and breastfeeding warnings in more detail.
Phentermine can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking Adipex-P. Take Adipex-P exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Talk with your doctor if you have increased hunger or if you otherwise think the medication is not working properly.
Taking more of this medication will not make it more effective and can cause serious, life-threatening side effects. Do not stop using Adipex-P suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using Adipex-P. Keep track of the amount of medicine used from each new bottle. Phentermine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Dosage Information in more detail. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. Seek emergency medical attention or call the Poison Help line at An overdose of phentermine can be fatal. Adipex-P may impair your thinking or reactions.
Be careful if you drive or do anything that requires you to be alert. Get emergency medical help if you have any of these signs of an allergic reaction to Adipex-P: This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Side effects in more detail. In some cases it may be desirable to give half tablets Adipex-P is not recommended for use in pediatric patients under 17 years of age.
Taking this medicine with other stimulant drugs that make you restless or hyperactive can worsen these effects.