Phentermine/topiramate side effects

By | 19.03.2018

phentermine/topiramate side effects

Roche Registration Limited; April Ephedrine Withdrawn from the US market due to adverse cardiovascular effects [27]. You must take a pregnancy test before you begin your treatment and once every month during your treatment. Your condition will not improve any faster, and your risk of side effects will increase. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses.

The majority of these events first occurred within the initial 12 weeks of drug therapy; however, in some patients, events were reported later in the course of treatments. In the Qsymia clinical trials, the overall prevalence of mood and sleep adverse reactions was approximately twice as great in patients with a history of depression compared to patients without a history of depression; however, the proportion of patients on active treatment versus placebo who reported mood and sleep adverse reactions was similar in these two subgroups.

Occurrence of depression-related events was more frequent in patients with a past history of depression across all treatment groups. However, the placebo-adjusted difference in incidence of these events remained constant between groups regardless of previous depression history. In the 1-year controlled trials of Qsymia, the proportion of patients who experienced one or more cognitive-related adverse reactions was 2.

These events typically began within the first 4 weeks of treatment, had a median duration of approximately 28 days or less, and were reversible upon discontinuation of treatment; however, individual patients did experience events later in treatment, and events of longer duration. In the 1-year controlled trials of Qsymia, the incidence of persistent low serum potassium values less than 3. Hypokalemia was reported by 0. In the 1-year controlled trials of Qsymia, there was a dose-related increase from baseline, peaking between Week 4 to 8, which declined but remained elevated over baseline over 1 year of treatment.

The incidence of increases in serum creatinine of greater than or equal to 0. In the 1-year controlled trials of Qsymia, the incidence of nephrolithiasis was 0. In the 1-year placebo-controlled clinical studies, The most common adverse reactions that led to discontinuation of treatment are shown in Table 4. The following adverse reactions have been reported during post approval use of phentermine and topiramate, the components of Qsymia.

Because these reactions are reported voluntarily from a population of uncertain size it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Euphoria , Psychosis , Tremor. Changes in libido , Impotence. Bullous skin reactions including erythema multiforme , Stevens-Johnson syndrome , toxic epidermal necrolysis , Pemphigus.

Hepatic failure including fatalities , Hepatitis. Last reviewed on RxList: Overview Professional Information Related Resources. Qsymia Side Effects Center. Find Lowest Prices on. Healthy Habits for Weight Loss Slideshow. Surprising Sources of Hidden Sugar. Weight Gain Shockers Slideshow. Stop taking this medication and call your doctor at once if you have a serious side effect such as: Less serious side effects may include: Mood and Sleep Disorders The proportion of patients in 1-year controlled trials of Qsymia reporting one or more adverse reactions related to mood and sleep disorders was Cognitive Disorders In the 1-year controlled trials of Qsymia, the proportion of patients who experienced one or more cognitive-related adverse reactions was 2.

Hypothermia [ Ref ]. Alopecia , rash Topiramate: Bullous skin reactions including erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis , pemphigus [ Ref ]. Dry mouth up to Nausea, diarrhea, gastroesophageal reflux disease , dyspepsia , oral paraesthesia, gastroenteritis Topiramate: Pancreatitis [ Ref ].

Dysmenorrhea, urinary tract infection [ Ref ]. Hepatic failure including fatalities , hepatitis [ Ref ]. Urticaria [ Ref ]. Influenza [ Ref ]. Back pain, extremity pain, muscle spasms, musculoskeletal pain, neck pain [ Ref ]. Upper respiratory tract infection up to Sinusitis, bronchitis, cough, sinus congestion, pharyngolaryngeal pain, nasal congestion [ Ref ]. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA. Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide. Obesity Alli , phentermine , liraglutide , amphetamine , Contrave , Saxenda , Adipex-P , Belviq , Qsymia , methamphetamine , garcinia cambogia , orlistat , More The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

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