Phentermine has pharmacologic activity similar to amphetamine d- and dll-amphetamine [ see Clinical Pharmacology Weigh the likely effectiveness of various treatments vs. Acidification of the urine increases Phentermine excretion. Common side effects for phentermine include dizziness, headache, trouble sleeping, overstimulation, restlessness, tremor, high blood pressure, palpitations, constipation, diarrhea, nausea, vomiting, and dry mouth. The medication has been associated with the development of valvular heart disease.
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|PHENTERMINE YOUTUBE BAD NEWS BEARS||Incorporate therapeutic integrative medicine modalities into clinical practice through the "Tools for Your Practice" section that offers how-to application for recommending mediation, prescribing probiotics, and how guidelines do an elimination diet. Can phentermine cause for dry eye syndrome? It didn't last long because they discovered the combination caused pulmonary damage. For more phentermine hcl 30mg how does it work information, consult with your doctor or ibuprofen for guidance based on your specific condition and current medications. Some patients who had received phentermine and fenfluramine or dexfenfluramine were found to have Primary Pulmonary Hypertension Guidelines or valvular heart disease. I just saw the dentist, a week ago, and they said my dosing are fine and no dental work for done. That is why I made the lifestyle change so ibuprofen I do stop taking dosing I phentermine continue with the weight loss.|
This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Based on the reported excretion of Phentermine in urine, exposure increases can be expected in patients with renal impairment [ see Clinical Pharmacology Use caution when administering Phentermine to patients with renal impairment.
Phentermine is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times than recommended.
Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes.
A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia. Manifestations of acute overdosage include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, and panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmia, hypertension or hypotension, and circulatory collapse.
Gastrointestinal symptoms include nausea, vomiting, diarrhea and abdominal cramps. Overdosage of pharmacologically similar compounds has resulted in fatal poisoning usually terminates in convulsions and coma. Management of acute Phentermine hydrochloride intoxication is largely symptomatic and includes lavage and sedation with a barbiturate. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard.
Acidification of the urine increases Phentermine excretion. The most severe manifestation of chronic intoxications is psychosis, often clinically indistinguishable from schizophrenia. See Drug Abuse and Dependence 9. Phentermine hydrochloride USP is a sympathomimetic amine anorectic. The structural formula is as follows:. Phentermine hydrochloride is a white, odorless, hygroscopic, crystalline powder which is soluble in water and lower alcohols, slightly soluble in chloroform and insoluble in ether.
Phentermine hydrochloride, an anorectic agent for oral administration, is available as a tablet containing Each tablet contains the following inactive ingredients: Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, amphetamine d- and dll-amphetamine. Drugs of this class used in obesity are commonly known as "anorectics" or "anorexigenics. Typical actions of amphetamines include central nervous system stimulation and elevation of blood pressure.
Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for. Following the administration of Phentermine, Phentermine reaches peak concentrations Cmax after 3 to 4. In a single-dose study comparing the exposures after oral administration of a combination capsule of 15 mg Phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg Phentermine capsule or a 92 mg topiramate capsule, there is no significant topiramate exposure change in the presence of Phentermine.
Studies have not been performed with Phentermine to determine the potential for carcinogenesis, mutagenesis or impairment of fertility. In relatively short-term clinical trials, adult obese subjects instructed in dietary management and treated with "anorectic" drugs lost more weight on the average than those treated with placebo and diet. The magnitude of increased weight loss of drug-treated patients over placebo-treated patients is only a fraction of a pound a week.
The rate of weight loss is greatest in the first weeks of therapy for both drug and placebo subjects and tends to decrease in succeeding weeks. The possible origins of the increased weight loss due to the various drug effects are not established. The amount of weight loss associated with the use of an "anorectic" drug varies from trial to trial, and the increased weight loss appears to be related in part to variables other than the drugs prescribed, such as the physician-investigator, the population treated and the diet prescribed.
Studies do not permit conclusions as to the relative importance of the drug and non-drug factors on weight loss. The natural history of obesity is measured over several years, whereas the studies cited are restricted to a few weeks' duration; thus, the total impact of drug-induced weight loss over that of diet alone must be considered clinically limited.
Dispense in a tight container as defined in the USP, with a child-resistant closure as required. Patients must be informed that Phentermine hydrochloride is a short-term a few weeks adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity, and that coadministration of Phentermine with other drugs for weight loss is not recommended [ see Indications and Usage 1 and Warnings and Precautions 5.
Patients must be instructed on how much Phentermine to take, and when and how to take it [ see Dosage and Administration 2 ]. Advise pregnant women and nursing mothers not to use Phentermine [ see Use in Specific Populations 8. The risks include, but are not limited to:. Tell patients to keep Phentermine in a safe place to prevent theft, accidental overdose, misuse or abuse. Selling or giving away Phentermine may harm others and is against the law.
Adipex-P , Lomaira , Ionamin , Suprenza. Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide. Obesity Alli , liraglutide , amphetamine , Contrave , Saxenda , Adipex-P , Belviq , Qsymia , methamphetamine , garcinia cambogia , orlistat , phendimetrazine , More The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Available for Android and iOS devices. My pharmacist said I should not take that kind of drug with my heart conditions. My doctor said it shouldn't have been a problem. Other patients worse than me are fine on it. Adipex-P phentermine is an appetite suppressant to help reduce weight in obese patients when used short-term and combined with exercise, diet, and behavioral modification. Phentermine is contraindicated in patients with cardiovascular disease. The cause of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known.
The possibility of an association between valvular heart disease and the use of Phentermine alone cannot be ruled out; there have been rare cases of valvular heart disease in patients who reportedly have taken Phentermine alone. For more specific information, consult with your doctor or pharmacist for guidance based on your specific condition and current medications. If I take generic phentermine, will I get the same results? Generic phentermine must meet the standard set forth by the FDA in order to be placed on the market.
As long as you are getting it from a local pharmacy and not on the Internet, there should not be any problem in taking the generics. This is a controlled substance, and you need a prescription for it, as you know. Medication from Internet web sites do not always give you the medications you are looking for even though they say they have a great price. How should I take phentermine so that it is absorbed the most quickly and is the most effective?
What makes it less effective? Phentermine is a stimulant. It is FDA-approved for short-term use in conjunction with diet and exercise for weight loss. According the manufacturer, phentermine should be administered before breakfast or 1 to 2 hours after breakfast. Alternatively, the tablet form may be divided in half and taken twice daily. It is best to avoid taking it late evening due to possible insomnia. In order to decrease appetite, most information recommends taking the drug 30 minutes before breakfast.
At the same time, in order to avoid some side effects, others suggest taking it with food. The alternate dosing of twice daily could be beneficial to prolong the effects throughout the day if your appetite returns in the afternoon. This may prove to make the phentermine more effective, but could also result in the difficulty sleeping. It is important follow the prescription exactly as written. If you want to make an adjustment, contact the prescriber before doing so.
Phentermine is related to a group of drugs known as amphetamines, and it's prescribed for short-term use to treat obesity. However, there are many serious side effects associated with phentermine. These include heart palpitations, hypertension, tachycardia abnormal heart rhythms , heart valve disease, primary pulmonary hypertension a dangerous lung disease , anxiety, restlessness, nervousness, insomnia, tremor, headache, dry mouth, diarrhea, constipation, and changes in libido. Phentermine also interacts adversely with many medications.
Lifestyle modifications that include a daily exercise routine and adopting healthy eating habits are safer alternatives to weight loss. Please consult with your physician and ask for a referral to a nutritionist who can assist you with permanent lifestyle modifications. Many years back, there was a Phen-phen diet pill craze. It didn't last long because they discovered the combination caused pulmonary damage.
I am hearing about Phentermine again, but not as the dynamic duo. I am thinking about going on it but want to be wise and safe. What is your recommendation about this "miracle" diet pill? Is it safe when used alone? Phentermine is a stimulant that is similar to an amphetamine. Phentermine is an appetite suppressant that affects the central nervous system.
It should be used short-term a few weeks , by itself for the treatment of obesity and should not be used in combination with any other diet medications. Phentermine should be combined with diet, exercise, and behavioral therapy. You should not take this medication if you have heart disease or moderate to severe high blood pressure; artheriosclerosis hardening of the arteries ; an overactive thyroid; glaucoma; if you are in an agitated state; or if you have a history of drug or alcohol abuse.
What are the side effects of phentermine? Your question concerns the side effects of phentermine. According to a drug interaction report performed by Lexi-Comp, there are no drug interactions detected with your phetermine Adipex P , Alli Orlistat and vitamin B12 cyanocobalamin. Your multivitamin could not be included in the drug interaction report because there are different multivitamin formulations and each vitamin would need to be analyzed to determine if there is a drug interaction.
It is known that Alli can decrease the absorption of some vitamins, mainly the fat soluble vitamins A, D ,E and K. The recommendation is to take the multivitamin at least two hours before or after taking Alli. A concern is that you are taking two separate medications for weight loss. Please make sure that your physician is okay with you taking both Phentermine and Alli.
As always, talk with your health care provider regarding questions you have about your medications. My doctor prescribed diet pills when I have high blood pressure and Grave's disease. One day I stopped breathing and they had to do CPR and use the paddles on me. At the hospital, they told my family that my heart was healthy, and that it was most likely the diet pills that the doctor had prescribed to me phentermine.
Do I have any recourse that I can take? Even if it was just to pay all my hospital bills, I had to have a pacemaker put in and can't drive for 6 months. We are truly sorry for your experience. There is a possibility that the medication may have exacerbated an existing condition or heart valve problem. Phenterrmine is similar to an amphetamine and should be prescribed with care, however it is impossible to know how anyone will react with it.
With this information, it is important to stay away from stimulants of any kind, including ephedrine, pseudoephedrine, excess caffeine, and other herbal stimulants. It is not our place to conclude any wrong doing by the physician or the drug manufacturer. However, I do recommend that you share your story in online patient forums. You may save someone's life. Please visit this link to see what other people have written about phentermine: Is taking phentermine okay for weight loss?
Phenteramine is marketed as a generic and under the brand names of Fastin, Ionamin, and Adipex. Phenteramine is an appetite suppressant of the amphetamine and phenethylamine drug class. It is approved as an appetite suppressant to help reduce weight in obese patients when used short-term and combined with exercise, diet, and behavioral modification. It is typically prescribed for individuals who are at increased medical risk because of their weight and works by helping to release certain chemicals in the brain that control appetite.
Some medical conditions are contra-indicated in taking phenteramine: Additionally, other medications may interact with phenteramine. You will need to provide a complete list of these medications for us to check for drug-drug interactions. Long-term use has the potential to cause psychological dependence. Recognizing the conditions listed above, I would say that phenteremine is safe to use when combined with a diet and exercise program.
For any immediate concerns, consult your physician. What is phentermine HCL, and is it safe in helping me to lose weight? It was developed in and given along with Pondimin fenfluramine or Redux dexfenfluramine , but the "fen-phen" combination resulted in serious heart valve conditions, so it is now given without the other two medications. Through increasing norepinephrine in specific pathways, the "fight or flight" response is activated and this reduces appetite. Studies have shown an average weight loss of 6.
The best way to lose weight is still considered to be through diet and exercise. For more information on medications, diet and nutrition, weight management, and healthy recipes, please visit our links at: I had taken phentermine Is this common or is this because I do drink coffee? I have since stopped taking the medication but it was helping me lose weight when I did take it.
Can you give me any advice? Phentermine is a medication that is used to assist with weight loss. This medication is a stimulant that works by suppressing the appetite. It is chemically related to amphetamines and may also increase metabolism. The prescribing information on phentermine does not list headache as a common side effect of this medication. The most common side effects are: You should consult with your physician about the severe headaches experienced while taking this medication.
Can phentermine cause severe dry eye syndrome? According to the prescribing information, dry eye was not a reported side effect associated with treatment with phentermine. If you have been experiencing symptoms of dry eye, consult with your health care provider for proper evaluation, diagnosis of the underlying cause and possible treatment options. Adipex phentermine is a stimulant appetite suppressant that affects the central nervous system. Phentermine is indicated for short term use together with diet and exercise to treat obesity.
Phentermine works best if taken on an empty stomach before breakfast or within 2 hours after breakfast. Phentermine can cause sleep problems, so take phentermine early in the day and no later than 6 pm. Take your dose of phentermine exactly as prescribed and never take more medication than what is recommended. Consult with your doctor if you are still hungry and you are concerned phentermine is not working effectively.
Phentermine should not be used in individuals with a history of heart disease, hyperthyroidism, or glaucoma. Common side effects associated with phentermine include elevated blood pressure, increased heart rate, dizziness, headache, restlessness, and dryness of the mouth. Phentermine has the potential for abuse. In addition, abrupt discontinuation of phentermine can result in extreme fatigue and mental depression.
This is not a complete list of side effects so consult with your doctor if you experience any unwanted side effects while taking phentermine. It is also important to let your doctor know if you take other prescription medications and any over-the-counter products. Over-the-counter products can include vitamins, supplements, and herbals.
Some products available over-the-counter could adversely react with phentermine and cause unwanted side effects or health conditions. Consult with your doctor or pharmacist before beginning any new medication or for guidance based on current medications. Phentermine is a prescription medication that is used for short-term weight loss. It is chemically related to amphetamines and works by suppressing the appetite and could have an effect on metabolism.
The prescribing information on phentermine does not specifically list nosebleeds as a side effect of the medication. However, this medication may cause an increase in blood pressure that could possibly lead to nosebleeds. The most common side effects of phentermine include: If you are experiencing nosebleeds and believe that the medication may be causing this side effect you should consult with your physician to be sure that your blood pressure is not elevated.
The physician will do a physical exam to see if any underlying conditions may be the cause of your nosebleed and offer suggestions for alleviating this symptom. Does phentermine affect the skin, making it drier? Some of the side effects associated with phentermine include: According to medical references, dry skin is not a common reported side effects associated with the use of phentermine. Consult your physician regarding the dry skin you are experiencing.
Is sweating a side effect of phentermine? Since I have started this medication, I sweat very easily and a lot. According to the prescribing information for phentermine, sweating was not a reported side effect of the medication. Some of the side effects of phentermine include overstimulation, restlessness, insomnia, dizziness, euphoria, diarrhea, unpleasant taste, constipation, changes in libido, tremor and headache.
This is not a complete list of side effects associated with phentermine. If you think you are experiencing a side effect from the medication, please consult with your health care provider for proper evaluation. According to the prescribing information, phentermine is indicated for short term use a few weeks as an adjunct therapy to diet, exercise, and behavioral modification to help lose weight.
Phentermine works by decreasing a person's appetite. Phentermine should not be used in people with severe high blood pressure, glaucoma, or a history of drug abuse. Phentermine should also not be used in people in agitated states or during, or within 14 days following, therapy with a monoamine oxidase inhibitor MAOI. Administration of phentermine and selective serotonin reuptake inhibitors SSRIs given together for weight loss is not recommended.
Some patients who had received phentermine and fenfluramine or dexfenfluramine were found to have Primary Pulmonary Hypertension PPH or valvular heart disease. PPH is a rare, but fatal lung disease. According to the prescribing information for phentermine, the possibility of PPH or valvular heart disease occurring with phentermine use alone cannot be ruled out. A person may become tolerant to the decreased appetite effect of phentermine within a few weeks.
The recommended dose should not be exceeded to overcome this effect, the drug is usually discontinued. Phentermine may impair the ability of a person to operate heavy machinery or drive a car. Phentermine and alcohol use may result in an adverse drug reaction. Phentermine should be used with caution in those with even mild high blood pressure. Phentermine, along with a dietary regimen, may alter insulin requirements.
I have taken phentermine and have had good success to lose weight after a pregnancy several years ago. I wanted to try it again but I am afraid of using it again because of any long-term effects it might have. Phentermine can cause sleep problems so take phentermine early in the day and no later than 6 pm.
Also, abrupt discontinuation of phentermine can result in extreme fatigue and mental depression. Phentermine may also be habit-forming and should be used only by the person it was prescribed for. Phentermine is only indicated for short-term use a few weeks. Phentermine should be used in conjunction with a reduced calorie diet and an increase in exercise. There are not long-term studies done on phentermine since it is only indicated for short-term use according to prescribing information. Talk to your doctor about the use of phentermine.
The doctor can determine the risk and benefits with the use of phentermine based on your current health condition.