The etiology of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known. Taking this medicine with other stimulant drugs that make you restless or hyperactive can worsen these effects. Get emergency medical help if you have any of these signs of an allergic reaction: If you experience any of the following symptoms, call your doctor immediately: Obesity Alli , liraglutide , amphetamine , Contrave , Saxenda , Adipex-P , Belviq , Qsymia , methamphetamine , garcinia cambogia , orlistat , phendimetrazine , More Dosage Information in more detail.
Phentermine is in a class of medications called anorectics. It works by decreasing appetite. Phentermine comes as tablets and extended-release capsules. It usually is taken as a single daily dose in the morning or three times a day 30 minutes before meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take phentermine exactly as directed. Most people takephentermine for 3 to 6 weeks; the length of treatment depends on how you respond to the medication.
Phentermine can be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period than your doctor tells you to. If you are taking the extended-release long-acting tablets, do not split, chew, or crush them tablet. There are some tablets that can be crushed and mixed with food. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. Follow the diet and exercise program your doctor has given you.
Phentermine works best in combination with a diet program. Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one. Phentermine may cause other side effects. Call your doctor if you have any unusual problems during your treatment with phentermine. Keep this medication in the container it came in, tightly closed, and out of reach of children.
Store it at room temperature and away from excess heat and moisture not in the bathroom. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. It is important to keep all medication out of sight and reach of children as many containers such as weekly pill minders and those for eye drops, creams, patches, and inhalers are not child-resistant and young children can open them easily.
To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location — one that is up and away and out of their sight and reach. In case of overdose, call the poison control helpline at Information is also available online at https: If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Keep all appointments with your doctor and the laboratory.
Your doctor will order certain lab tests to check your response to phentermine. Dispense in a tight container. Keep out of the reach of children. Overstimulation, restlessness, dizziness, insomnia, euphoria , dysphoria , tremor , headache; rarely psychotic episodes at recommended doses with some drugs in this class. Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances.
Impotence , changes in libido. In a single-dose study comparing the exposures after oral administration of a combination capsule of 15 mg phentermine and 92 mg topiramate to the exposures after oral administration of a 15 mg phentermine capsule or a 92 mg topiramate capsule, there is no significant topiramate exposure change in the presence of phentermine. The safety and efficacy of combination therapy with phentermine and any other drug products for weight loss, including selective serotonin reuptake inhibitors e.
Therefore, the coadministration of these drug products for weight loss is not recommended. Primary Pulmonary Hypertension PPH — a rare, frequently fatal disease of the lungs — has been reported to occur in patients receiving a combination of phentermine with fenfluramine or dexfenfluramine. The possibility of an association between PPH and the use of phentermine alone cannot be ruled out.
The initial symptom of PPH is usually dyspnea. Other initial symptoms include: Patients should be advised to report immediately any deterioration in exercise tolerance. Treatment should be discontinued in patients who develop new, unexplained symptoms of dyspnea, angina pectoris, syncope, or lower extremity edema.
The etiology of these valvulopathies has not been established and their course in individuals after the drugs are stopped is not known. IONAMIN may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly. When using CNS active agents, consideration must always be given to the possibility of adverse interactions with alcohol.
IONAMIN is related chemically and pharmacologically to amphetamine d- and dl-amphetamine and other stimulant drugs that have been extensively abused. The possibility of abuse of IONAMIN should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program. Abuse of amphetamine d- and dl-amphetamine and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of some of these drugs to many times that recommended.
Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity , and personality changes.
The most severe manifestation of chronic intoxications is psychosis , often clinically indistinguishable from schizophrenia. Safe use in pregnancy has not been established. Use of IONAMIN by women who are or may become pregnant requires that the potential benefit be weighed against the possible hazard to mother and infant. The least amount feasible should be prescribed or dispensed at one time in order to minimize the possibility of overdosage.
Clinical studies of IONAMIN did not include sufficient numbers of subjects aged 65 or over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.
This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. Manifestations of acute overdosage may include restlessness, tremor , hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, panic states.
Cardiovascular effects include arrhythmias, hypertension , or hypotension and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps.